Category Archives: genomics

Sweptaway – Part 1

Posted on 3 Sep, 2015 by Arun Sethuraman

Brace yourselves for a series of new posts on selection, especially with articles from the special Molecular Ecology issue on “Detecting selection in natural populations: making sense of genome scans and towards alternative solutions” starting to roll out! Selective sweeps … Continue reading →

Posted in adaptation, evolution, genomics, mutation, population genetics, selection, speciation, theory | Tagged , , , , , | Leave a comment

And who made your beer?

Posted on 27 Aug, 2015 by Arun Sethuraman

In the spirit of it being almost Friday, and while we’re on the topic of your favorite beverages – perhaps wine puts you to sleep, couldn’t care less where it came from, but prefer the bitterness of lager beers at your … Continue reading →

Posted in adaptation, evolution, genomics, natural history, next generation sequencing, phylogenetics, population genetics, selection, speciation, yeast | Tagged , , , , | 2 Comments

The unforeseen genomic consequences of domestication

Posted on 26 Aug, 2015 by Rob Denton

When a desired genome is selected for propagation, all mutations, beneficial, neutral, or deleterious, shift in frequency, and this sometimes can have unforeseen consequences. Natural selection takes the good with the bad. Beneficial and harmful mutations combine to provide a net … Continue reading →

Posted in domestication, genomics, plants, selection, transcriptomics | Tagged , | Leave a comment

Where's your wine from?

Posted on 20 Aug, 2015 by Arun Sethuraman

Human-mediated selection of yeast cultures has played a huge role in the development of numerous unique strains of Sacchromyces cerevisiae, often attributed to production of a wide variety of wines the world over. Previous studies have indicated a single domesticated … Continue reading →

Posted in domestication, evolution, genomics, horizontal gene transfer, microbiology, Molecular Ecology, the journal, next generation sequencing, phylogenetics, phylogeography, population genetics, STRUCTURE, yeast | Tagged , , , | 1 Comment

Notes from Edmonton and #Botany2015

Posted on 11 Aug, 2015 by Jeremy Yoder

As noted previously, I broke with my usual habit and skipped the Evolution meetings this year. Instead, I attended Botany 2015, a joint meeting of multiple U.S. and Canadian plant-focused scholarly societies held in Edmonton, Alberta — I’d never been … Continue reading →

Posted in bioinformatics, conferences, genomics, natural history, phylogenetics, plants, population genetics | Tagged | 1 Comment

Selection scans, and the genomics of adaptive/maladaptive introgression

Posted on 6 Aug, 2015 by Arun Sethuraman

Natural selection, and the adaptive evolution of hybrid reproductive incompatibilities post divergence are known to be major drivers of speciation. At the phenotype level, these manifest as fitness differences between introgressing populations. At the genomic level, speciation “genes” or “islands” … Continue reading →

Posted in adaptation, Coevolution, evolution, genomics, Molecular Ecology, the journal, mutation, natural history, population genetics, selection, speciation, theory | Tagged , , , , | 3 Comments

PCA of multilocus genotypes in R

Posted on 30 Jul, 2015 by Arun Sethuraman

An earlier post from Mark Christie showed up on my feed on calculating allele frequencies from genotypic data in R, and I wanted to put together a quick tutorial on making PCA (Principal Components Analysis) plots using genotypes. I used … Continue reading →

Posted in bioinformatics, genomics, howto, population genetics, R, software | Tagged , , | 6 Comments

Who came first – the Paleo- or Native American?

Posted on 23 Jul, 2015 by Arun Sethuraman

In yet another infamous Science vs Nature race, two studies published this Tuesday toss more cans of worms at the ongoing debate about the founding of the Americas – with disparate findings. Uh oh. Skoglund et al. Nature (2015) Genetic … Continue reading →

Posted in genomics, next generation sequencing, Paleogenomics, population genetics | Tagged , , , , | 2 Comments

What do with all those pesky mtDNA reads in your NGS experiment

Posted on 21 Jul, 2015 by Noah Snyder-Mackler

Have you ever noticed how many reads from your high throughput sequencing project map to the tiny fraction of your genome that is the mitochondrial genome (mtDNA)? Pretty much any NGS experiment (e.g., RNA-seq, DNA-seq, capture-based sequencing) leave you with … Continue reading →

Posted in bioinformatics, genomics, howto, mutation, software, Uncategorized | Tagged , | Leave a comment

IMa2p – Parallel Isolation with Migration Analyses

Posted on 16 Jul, 2015 by Arun Sethuraman

I figured that it was time to write an update on my post from a year ago on Bayesian MCMC in inferring ancestral demography. Recently, my postdoctoral advisor, Jody Hey and I released a version of the popular IMa2 program, … Continue reading →

Posted in bioinformatics, genomics, howto, software, theory | Tagged , , , , , | 1 Comment