Category Archives: genomics

What is DAS? A new tool to recover genomes from metagenomes

There are a lot of data out there, and if you haven’t already noticed the ‘omics train has steadily stayed its path through the fruitful (but challenging) world of metagenomics. Metagenomics offers the chance to unravel complex microbial communities without … Continue reading

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Posted in bioinformatics, community ecology, genomics, metagenomics, methods, microbiology, next generation sequencing | Tagged , , , | Leave a comment

Chromosomal inversions and the maintenance of species barriers

Chromosomal inversions have long fascinated evolutionary biologists for their role in adaptation and speciation. These structural variants are abundant in natural populations and can have diverse evolutionary consequences. They can cause reproductive isolation through hybrid sterility or protect sets of … Continue reading

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DNA extraction for PacBio sequencing

PacBio is emerging as the favoured sequencing approach for assembling high-quality reference genomes. But the big issue with PacBio sequencing is that to get long sequence reads you need to start with high molecular weight DNA. For my first foray … Continue reading

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Sequencing round-up 2018

The deluge of new sequencing approaches continues at a pace. It seems that you turn your back for five minutes and there’s a shiny new sequencing platform promising to deliver more for less. What is the current state of play … Continue reading

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Posted in genomics, next generation sequencing | Tagged , , , | 1 Comment

Oh my ploidy … diploids evolve more slowly than haploids?

It’s been an embarrassingly long time since I last sat at my keyboard in a TME capacity (#NewPI chat doesn’t really count)! One year ago today, to be exact (writing this on 28 March, for publication on 29 March). Thus, … Continue reading

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Posted in adaptation, blogging, evolution, genomics, haploid-diploid, selection, yeast | Tagged , , , , , , | Leave a comment

Major new microbial groups expand diversity and alter our understanding of the tree of life

I still believe in revolutions. And sometimes they just happen, almost unnoticed. One such revolution happened on a boring 11th of April 2016 when Laura Hug et al. published their new tree of life in the journal of Nature Microbiology. … Continue reading

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Posted in bioinformatics, community ecology, evolution, genomics, metagenomics, microbiology, next generation sequencing, phylogenetics | Tagged , , , , , , , | Leave a comment

Are population genomic scans for locally adapted loci too successful?

Last Friday, Molecular Ecology released an interesting new systematic review online ahead of print. Colin Ahrens and coauthors at a number of Australian research institutions compiled results from 66 papers reporting tests for locally adapted loci based on either FST … Continue reading

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Genomic signatures of ancient rendezvous and separation in elephant evolution

Evidence from various levels of the tree of life is showing that we’ve been picturing ancient encounters between related species all wrong and admixture events are probably more common than expected. Even rendezvous among primates, caniforms, and majestic proboscideans often … Continue reading

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Posted in conservation, evolution, genomics, hybridization, natural history, Paleogenomics, phylogeography | Tagged , , , , , , | Leave a comment

Exploring the genomic diversity of tubeworm endosymbionts

Tubeworms are cool. (To be read only in your best (eleventh) Doctor Who voice). Although, depending on how close they are to a hydrothermal vent, they might be more on the hot side….Regardless, if you’re on the fence about how … Continue reading

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Posted in bioinformatics, Coevolution, community ecology, evolution, genomics, metagenomics, microbiology | Tagged , , | Leave a comment

Climate change and genomic vulnerability

As the world burns and we barrel heedlessly into an ever-smaller and uglier future, predicting how species will respond to climate change will be critical for conservation planning. Intuition suggests most organisms will shift their ranges up in latitude or … Continue reading

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Posted in conservation, evolution, genomics | Tagged | 1 Comment