Tag Archives: whole-genome sequencing

Can small populations benefit genetic rescue?

The core dogma of conservation biology is clear: small populations are bad for species’ persistence. If we observe a population of endangered vertebrates harboring abundant deleterious mutations but without any reduction in fitness, what is happening there? I would like … Continue reading

Posted in conservation, genomics, mammals, mutation, population genetics, theory | Tagged , , , , , , , , , , , | Leave a comment

They joy of genome sequencing: when genomics meets natural history

When I have a massive pile of papers that I need to read, I can’t help but look at the ones with interesting natural history first. There’s something exceptionally satisfying about using modern tools to dig deeper into the features … Continue reading

Posted in evolution, genomics, RNAseq, transcriptomics | Tagged , | Leave a comment

To RADseq or not to RADseq?

It’s a cliche to say that we live in a moment of unprecedented possibility for molecular ecology, as high-throughput sequencing methods drive the cost of collecting DNA sequence data ever lower. But at the same time, it’s a tricky moment, … Continue reading

Posted in adaptation, association genetics, genomics, methods, next generation sequencing, selection | Tagged , , , , | 8 Comments