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Author Archives: Alex Twyford
Evolution 2018: assortative mating, combinatorial speciation and genome dynamics
The Evolution conference in Montpellier is over, and as the sun, wine and great science become a memory, here is my recap of some conference highlights following on from a great first day: A sea of scientists waiting for a … Continue reading
Evolution 2018 Day 1: From genomics in the wild, to new models of selection
It’s Evolution conference time! Evolution has long been my favourite fixture in the conference calendar, with its diverse mix of theoretical and empirical studies that span the full range of evolutionary biology. This year it’s the second Joint Congress on … Continue reading
Posted in adaptation, community, conferences, evolution, genomics, population genetics, speciation, theory
Tagged #Evol2018, Evolution 2018, Montpellier
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They joy of genome sequencing: when genomics meets natural history
When I have a massive pile of papers that I need to read, I can’t help but look at the ones with interesting natural history first. There’s something exceptionally satisfying about using modern tools to dig deeper into the features … Continue reading
Posted in evolution, genomics, RNAseq, transcriptomics
Tagged natural history, whole-genome sequencing
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Chromosomal inversions and the maintenance of species barriers
Chromosomal inversions have long fascinated evolutionary biologists for their role in adaptation and speciation. These structural variants are abundant in natural populations and can have diverse evolutionary consequences. They can cause reproductive isolation through hybrid sterility or protect sets of … Continue reading
Posted in adaptation, genomics, hybridization, next generation sequencing, speciation
Tagged chromosome structure, inversions
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DNA extraction for PacBio sequencing
PacBio is emerging as the favoured sequencing approach for assembling high-quality reference genomes. But the big issue with PacBio sequencing is that to get long sequence reads you need to start with high molecular weight DNA. For my first foray … Continue reading
Posted in genomics, next generation sequencing, Uncategorized
Tagged DNA extraction, museum genomics, PacBio, quality control
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Sequencing round-up 2018
The deluge of new sequencing approaches continues at a pace. It seems that you turn your back for five minutes and there’s a shiny new sequencing platform promising to deliver more for less. What is the current state of play … Continue reading
Posted in genomics, next generation sequencing
Tagged BGISEQ, Illumina sequencing, MinION, PacBio
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