Tag Archives: mitochondria

Free to go but required to stay: contrasting views on mitochondrial relationships

Ever since a bacterium found itself mysteriously engulfed in our eukaryotic ancestor, things have been, uh, complicated regarding our two genomes. One is big, one is small. One is circular, one is linear. One is numerous in each cell, the … Continue reading

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What do with all those pesky mtDNA reads in your NGS experiment

Have you ever noticed how many reads from your high throughput sequencing project map to the tiny fraction of your genome that is the mitochondrial genome (mtDNA)? Pretty much any NGS experiment (e.g., RNA-seq, DNA-seq, capture-based sequencing) leave you with … Continue reading

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