Tag Archives: GWAS

Recent reading: 18 Sept 2022

Los Angeles doesn’t really get full-on summer heat until September, after months of building warmth and time elapsed since that last gasp of winter rains and spring fog. This year we (and most of the rest of the western U.S.) … Continue reading

Posted in ecology, evolution, journal club | Tagged , , , | Leave a comment

Still ruffling feathers after all these years: Darwin's finches and a molecular view of adaptive radiation

One of the many lovely things about molecular ecology is its ability to shine new light on old stories. The well-known case of Darwin’s finches is a classic example of adaptive radiation. These finches demonstrate a clear instance where over time, … Continue reading

Posted in adaptation, association genetics, evolution, genomics, Molecular Ecology, the journal, population genetics, RNAseq, selection, speciation | Tagged , , | 2 Comments

WTF (What's The Function?)

Jay Shendure’s editorial, “Life after genetics”, points out that we, as geneticists, should shift our focus from variant-finding (e.g., GWAS) to understanding the functional implications of disease-associated variants: “We are in a period of rich discovery in human genetics and genomics. The … Continue reading

Posted in genomics, medicine, mutation, next generation sequencing | Tagged , , , | Leave a comment

On “triangulation” in genome scans

Guest contributor K.E. Lotterhos is a marine biologist at Wake Forest University, who studies evolutionary responses to fishing and climate change. You can find her on Twitter under the handle @dr_k_lo. A major goal of evolutionary biology is to understand the genetic … Continue reading

Posted in adaptation, association genetics, genomics, methods, population genetics, quantitative genetics | Tagged , , , | 7 Comments