Tag Archives: GWAS

Still ruffling feathers after all these years: Darwin's finches and a molecular view of adaptive radiation

One of the many lovely things about molecular ecology is its ability to shine new light on old stories. The well-known case of Darwin’s finches is a classic example of adaptive radiation. These finches demonstrate a clear instance where over time, … Continue reading

Posted in adaptation, association genetics, evolution, genomics, Molecular Ecology, the journal, population genetics, RNAseq, selection, speciation | Tagged , , | 2 Comments

WTF (What's The Function?)

Jay Shendure’s editorial, “Life after genetics”, points out that we, as geneticists, should shift our focus from variant-finding (e.g., GWAS) to understanding the functional implications of disease-associated variants: “We are in a period of rich discovery in human genetics and genomics. The … Continue reading

Posted in genomics, medicine, mutation, next generation sequencing | Tagged , , , | Leave a comment

On “triangulation” in genome scans

Guest contributor K.E. Lotterhos is a marine biologist at Wake Forest University, who studies evolutionary responses to fishing and climate change. You can find her on Twitter under the handle @dr_k_lo. A major goal of evolutionary biology is to understand the genetic … Continue reading

Posted in adaptation, association genetics, genomics, methods, population genetics, quantitative genetics | Tagged , , , | 7 Comments