Tag Archives: genome

A solution to the N50 misassembly problem

This is the fifth in a series of posts where we explain the N50 (Nx) metric, discuss the problems surrounding it, give solutions to those problems, and suggest an alternative N50 metric for transcriptome assemblies. The misassembly problem of N50 that … Continue reading

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A solution to the N50 filtering problem

This is the fourth in a series of posts where we explain the N50 (Nx) metric, discuss the problems surrounding it (1, 2), give solutions to those problems, and suggest an alternative N50 metric for transcriptome assemblies. In the two … Continue reading

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The N50 misassembly problem

This is the third in a series of posts where we explain the N50 (Nx) metric, discuss the problems surrounding it, give solutions to those problems, and suggest an alternative N50 metric for transcriptome assemblies. In our previous post, we … Continue reading

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The N50 filtering problem

This is the second in a series of posts where we explain the N50 (Nx) metric, discuss the problems surrounding it, give solutions to those problems, and suggest an alternative N50 metric for transcriptome assemblies. The problem with N50 (or … Continue reading

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Posted in genomics | Tagged , , | 1 Comment

What’s N50?

This is the first in a series of posts where we explain the N50 (Nx) metric, discuss the problems surrounding it, give solutions to those problems, and suggest an alternative N50 metric for transcriptome assemblies. Most genome assembly papers include … Continue reading

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Posted in genomics | Tagged , , | 5 Comments

Chromosomal inversion determines male morphs in the ruff

The ruff is a wading bird where the male becomes especially spectacular during mating season with its colorful and variable breeding plumage. Two papers published together in Nature Genetics in November have now identified the genetic source of the large variation … Continue reading

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There and back again: an angiosperm’s tale

Eelgrass (Zostera marina) is the dominant seagrass in the northern hemisphere and provides the foundation of highly productive ecosystems that rival tropical rain forests and coral reefs in ecosystem services. Zostera isn’t really a grass, but a monocot, like a … Continue reading

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Posted in adaptation, bioinformatics, community ecology, evolution, genomics, plants | Tagged , , , , | Leave a comment