Table 3c. Error rates for announced & commercially available DNA sequencing platforms in February 2012. All Error rates are in percentage. Percentage of errors per base within single reads of the maximum length. As explained in Glenn (2011), error rates among platforms are not exactly comparable. The reported Ion Torrent rates range from 0.46% to 2.4%. Final Error rates SOLiD rates are from reads with bases consistent on double or triple sequencing only. Final Error rate for PacBio applies only to the consensus sequencing for three independent reads of the same template. For Illumina, errors at ≤0.1% is achieved for ≥ 85% of reads (not all reads). See Glenn (2011) for additional details.
|Primary Errors||Single-pass Error Rate (%)||Final Error Rate (%)|
|454 All models||Indel||1||1|
|Illumina All Models||Substitution||~0.1||~0.1|
|Ion Torrent – all chips||Indel||~1||~1|
|SOLiD – 5500xl||A-T bias||~5||≤0.1|
|PacBio RS||CG deletions||~15||≤15|
* Information based on company sources alone (independent data not yet available); it is not clear if the 4% error rate reported by Oxford Nanopore refers to a single-pass rate or is what is achieved after reading both strands & producing a consensus sequence.