Tag Archives: whole-genome sequencing

How do you use genome-wide diversity in conservation?

Measuring how genome-wide diversity matters to threatened species has been a constant endeavor of conservation genetics, and still is in the era of genomics. But what should we do with the fact that it often do not correlate with IUCN Red List categories, a measure of species’ threat status? Continue reading

Posted in conservation, demography, evolution, genomics, mammals, population genetics, Uncategorized | Tagged , , , , , , | Leave a comment

Can small populations benefit from genetic rescue?

The core dogma of conservation biology is clear: small populations are bad for species’ persistence. If we observe a population of endangered vertebrates harboring abundant deleterious mutations but without any reduction in fitness, what is happening there? I would like … Continue reading

Posted in conservation, genomics, mammals, mutation, population genetics, theory | Tagged , , , , , , , , , , , | 1 Comment

They joy of genome sequencing: when genomics meets natural history

When I have a massive pile of papers that I need to read, I can’t help but look at the ones with interesting natural history first. There’s something exceptionally satisfying about using modern tools to dig deeper into the features … Continue reading

Posted in evolution, genomics, RNAseq, transcriptomics | Tagged , | Leave a comment

To RADseq or not to RADseq?

It’s a cliche to say that we live in a moment of unprecedented possibility for molecular ecology, as high-throughput sequencing methods drive the cost of collecting DNA sequence data ever lower. But at the same time, it’s a tricky moment, … Continue reading

Posted in adaptation, association genetics, genomics, methods, next generation sequencing, selection | Tagged , , , , | 8 Comments