Tag Archives: population genetics

Divergence and Linked Background Selection

We have widely discussed the reduction in neutral diversity due to demography and linked selection effects (e.g. selective sweeps and hitchhiking, or background selection) in several previous posts (e.g see here, here, and here). However, how linked selection affects neutral divergence … Continue reading

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On (mis)interpreting STRUCTURE/ADMIXTURE results

STRUCTURE, ADMIXTURE and other similar software are among the most cited programs in modern population genomics. They are algorithms that estimate allele frequencies and admixture proportions under the premise that sampled genotypes are derived from one of “K” ancestral populations, … Continue reading

Posted in bioinformatics, genomics, howto, methods, population genetics, software, STRUCTURE | Tagged , , , , | 1 Comment

What do dolphins, bivalves and algae have in common?

Collaboration as it turns out, between three scientists interested in vertebrates, invertebrates and algae! A few days before we left for Evolution 2016 in Austin, one of my collaborators, Eric Pante, came to Charleston as the final stop in a North American … Continue reading

Posted in bioinformatics, blogging, career, conferences, DNA barcoding, haploid-diploid, natural history, phylogenetics, phylogeography, population genetics | Tagged , , , , , | Leave a comment

The Great Migration and African-American Genomic History

Over 45 million African-Americans share a recent common history largely shaped by “The Great Migration” (1910-1970) from out of the Southern United States. And yet, the admixture history of the African-American community, and its consequences for public health are little … Continue reading

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Ice-Age Euro-trips

Recent works that attempt to get at human migrations inside Europe paint a complex portrait of migratory events, admixture with archaic hominids, and adaptive evolution to new geographies, and a changing global climate. Analyzing whole genomes of 51 ancient humans … Continue reading

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Signatures of the reproductive lottery

In marine populations, effective population sizes are usually several orders of magnitude lower than the census size. This difference is thought to be driven by high fecundity, variation in reproductive success and pronounced early mortality, resulting in genetic drift across generations. In … Continue reading

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What does the island fox say?

Small populations are characterized by large drift and reduced efficacy of selection effects, which result in fixation of both advantageous and deleterious alleles, accumulation of homozygosity, and often reduction in population fitness. What with plummeting mammal populations across biota, understanding … Continue reading

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