Tag Archives: genome-editing

The almighty CRISPR-Cas9 technology: How does it work?

CRISPR-Cas9 took the whole world of biology by storm. Selected Science’s 2015 Breakthrough of the Year, the CRISPR-Cas9 technology is revolutionizing science. Within five years of the official announcement (Jinek et al. 2012), it became the genome-editing technique of choice. … Continue reading

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Posted in evolution, genomics, methods, theory | Tagged , , , | 2 Comments

WTF (What’s The Function?)

Jay Shendure’s editorial, “Life after genetics”, points out that we, as geneticists, should shift our focus from variant-finding (e.g., GWAS) to understanding the functional implications of disease-associated variants: “We are in a period of rich discovery in human genetics and genomics. The … Continue reading

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Posted in genomics, medicine, mutation, next generation sequencing | Tagged , , , | Leave a comment