Category Archives: software

STITCH, in time, could save a lot of array design

A new algorithm for processing DNA sequence data, STITCH, could lower costs for studies of genetic variation within species by reconstructing, or “imputing”, the sequences of individual samples within a larger dataset. The ongoing proliferation of high-throughput (or, ugh, “next … Continue reading

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Making Maps in R, volume 2: ggplots

The open-source statisical programming environment R is truly a Swiss Army knife for molecular ecology. With the right code, R can processes genetic data and trait measurements, analyze how genetic variants relate to traits, reconstruct phylogenetic trees, and illustrate the … Continue reading

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Data, data everywhere and another tool to use: Taxonomer, a web-tool for metagenomics data analysis

Because sequencing. With all the affordable genome and metagenome sequencing available, we’ve reached an unprecedented point at which we can profile microbial communities more accurately than ever before. For this reason, it’s essential to develop efficient methods for data analysis. … Continue reading

Posted in bioinformatics, community ecology, genomics, metagenomics, methods, microbiology, software | Tagged , , , | Leave a comment

Poorly updated databases will affect your results

If you’re anything like me, your research is heavily dependent on the many wonderful database resources available online. NCBI, UniProtKB, Ensembl, Swiss-Prot, EMBL-EBI, and many other sites and organizations offer highly useful (and often curated) molecular information. Can you imagine … Continue reading

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Docker: making our bioinformatics easier and more reproducible

This is a guest post by Alicia Mastretta-Yanes, a CONACYT Research Fellow assigned to CONABIO, Mexico. Her research uses molecular ecology and genomic tools to examine the effect of changes on species distributions due to historical climate fluctuations as well … Continue reading

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On Integrative Species Delimitation…

Accurate delimitation of species is a fundamental first step that underlies much of what we do in biology. But this can prove challenging in many situations. Why? Let me count the ways. Incomplete lineage sorting, hybridization, morphological conservatism, and niche … Continue reading

Posted in evolution, methods, phylogeography, population genetics, software, species delimitation | Leave a comment

A new (quantitative!) method for comparative phylogeography

Comparative phylogeographic studies usually involve a) documenting a phylogeographic pattern and b) recognizing that the same pattern is congruent in multiple species. But what if species histories are only sortof congruent? Perhaps they share one major splitting event but not later … Continue reading

Posted in Coevolution, phylogeography, plants, software | Tagged , | 5 Comments