Category Archives: genomics

Molecular Inversion Probes: phylogenomics without the excess?

The onset of the phylogenomic era has revolutionized molecular ecology and systematics, helping resolve relationships throughout the tree of life that have long eluded researchers working with only a handful of loci and morphological data. Phylogenetic studies of nonmodel organisms … Continue reading

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Posted in genomics, next generation sequencing, phylogenetics, phylogeography, population genetics, transcriptomics | Tagged , | Leave a comment

STITCH, in time, could save a lot of array design

A new algorithm for processing DNA sequence data, STITCH, could lower costs for studies of genetic variation within species by reconstructing, or “imputing”, the sequences of individual samples within a larger dataset. The ongoing proliferation of high-throughput (or, ugh, “next … Continue reading

Posted in association genetics, bioinformatics, genomics, methods, next generation sequencing, software | Tagged | Leave a comment

Who’s really riding the subway with you? Characterization of the microbial communities on Boston transport

(Figure modified from Hsu et al., 2016, Boston transport map and wikicommons image of Boston) Understanding the microbes around us is an important challenge to take on. There have been articles covering changes in microbial communities among rural and more … Continue reading

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New insight into the genetic basis of industrial melanism

The evolution of coloration in peppered moths during the industrial revolution is one of the most well known examples of natural selection in action. Part of the appeal of the system is the apparent simplicity. The once-abundant light colored morph … Continue reading

Posted in adaptation, association genetics, genomics, mutation, selection | Leave a comment

Microbes are going to infinity and beyond! Monitoring community changes on a simulated space station

As we’ve discussed previously here, understanding microbes in the natural and built environment around us, has implications related to human health and disease. It has turned out to be pretty tricky to clarify what is going on with our most … Continue reading

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Mitogenomes from extinct New Zealand wrens shed light on the oldest songbird lineage

The order Passeriformes, commonly known as “perching birds” or “songbirds,” contains over half of all known avian species. Sister to all other Passeriformes are the acanthisittid wrens, a small and enigmatic family of New Zealand endemics. Though their providential phylogenetic … Continue reading

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The Great Migration and African-American Genomic History

Over 45 million African-Americans share a recent common history largely shaped by “The Great Migration” (1910-1970) from out of the Southern United States. And yet, the admixture history of the African-American community, and its consequences for public health are little … Continue reading

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