Category Archives: bioinformatics

We have the technology. Is sequencing getting better, smaller, faster?

Okay, I know some version of the phrase “recent developments in rapid and affordable sequencing have made blah blah blah possible…” is something you’ve probably read 10,000 times. However, third-generation sequencing platforms have turned out to be pretty darn astounding. … Continue reading

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Non-model organisms are so hot right now

What makes a model organism? Well, as the name suggests, they are widely studied and have been adapted to a vast array of common genetic techniques. A few of the most often utilized organisms, which you are most likely already … Continue reading

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The largest mammalian genome is not polyploid

Some 40 million years ago in South America, following the arrival of the common ancestor of caviomorph rodents from the Old World, big changes were afoot. Specifically, the caviomorph colonists were beginning to give rise to an extant evolutionary progeny … Continue reading

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Easily aggregate bioinformatic sample output with one tool

Today I’m going to write about one of my favorite bioinformatic tools, MultiQC. If you’ve used it, you know why, and if you haven’t, prepare to be amazed. Many bioinformatic software produce output on a per-sample basis. That is, you … Continue reading

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Shared patterns of genomic diversity across populations of distantly related taxa

Genomic diversity is shaped by the complex interplay between the effects of genetic drift and natural selection among populations. Several of these effects, especially those of linked selection at neutral sites, adaptive introgression, and barriers to migration (often called “genomic … Continue reading

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Mapping genomes and navigating behavior for wildlife conservation

Virginia Aida wrote this post as a final project for Stacy Krueger-Hadfield’s Science Communication course at the University of Alabama at Birmingham. She is currently evaluating a potential pharmacotherapy in traumatic brain injury and anticipates graduating with her MS in summer 2017.  Although she … Continue reading

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Posted in adaptation, association genetics, bioinformatics, blogging, conservation, domestication, evolution, natural history | Tagged , , , , , , | Leave a comment

Small Molecules, Big Differences

Mary Latimer wrote this post as a final project for Stacy Krueger-Hadfield’s Science Communication course at the University of Alabama at Birmingham. She is a third year PhD student at UAB studying miRNAs and methionine restriction. Her hobbies include cats, netflix, … Continue reading

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Posted in bioinformatics, blogging, evolution, genomics, natural history, next generation sequencing, RNAseq | Tagged , , , , | Leave a comment