Monthly Archives: October 2012

One of these flycatchers is not like the other …

When you think about it, an awful lot of the things you can do with a genome sequence amount to lining it up next to another genome sequence, and then listing all the places where they differ. That’s more or … Continue reading

Posted in next generation sequencing, speciation | Leave a comment

What we're reading

As we head into the weekend, here’s a few things we’ve noticed that might be worth your screen-time. In the journals Zhen, Y., M. L. Aardema, E. M. Medina, M. Schumer and P. Andolfatto. 2012. Parallel molecular evolution in an … Continue reading

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Molecular Ecology Online Forum, 2012

Welcome to the Molecular Ecologist Online Forum, which brings together panelists from the Molecular Ecologist Symposium at the Ottawa 2012 Joint Congress on Evolutionary Biology to continue that meeting’s fruitful discussion. (Video and slides from that symposium are available online … Continue reading

Posted in conferences, methods, next generation sequencing, population genetics | 3 Comments

What we're reading, and zooming

As we head into the weekend, here’s a few things we found this week that might be worth your screen time: In the journals: Minoche, A. E., J. C. Dohm and H. Himmelbauer. 2011. Evaluation of genomic high-throughput sequencing data … Continue reading

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Linux: the glue that binds your next-generation sequencing analyses

Would you like to use same operating system as 92% of the top 500 super computers?  Do you dig Japanese bullet trains, NASA, or the financial awesomeness that is the New York Stock Exchange?  Do you hate having to shell … Continue reading

Posted in bioinformatics, next generation sequencing, population genetics | 5 Comments

What we're reading

As we head into the weekend, here’s a few things we found this week that might be worth your screen time: In the journals Calcagno, V., E. Demoinet, K. Gollner, L. Guidi, D. Ruths and C. de Mazancourt. 2012. Flows … Continue reading

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Best Practices for Scientific Computing…And Molecular Ecology?

Source: http://xkcd.com/292 *Update* Best Practices in Computing has now been published in PLoS Biology! Computers and computational techniques have significantly advanced the molecular ecologist’s toolbox for answering interesting and complex questions about a range of biological systems,  model or otherwise. Imagine, … Continue reading

Posted in bioinformatics, data archiving, population genetics, science publishing, software | Tagged | 1 Comment

What we're reading

As we head into the weekend, here’s a few things we found this week that might be worth your screen time: In the journals Maughan, H., P. W. Wang, J. Diaz Caballero, P. Fung, Y. Gong, S. L. Donaldson, L. … Continue reading

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Dramatically reducing sequencing error via Duplex Tag sequencing

An exciting new study was published in PNAS last month, an open access paper entitled “Detection of ultra-rare mutations by next-generation sequencing”. This new method has the potential to open up a new frontier in Next-gen sequencing bioinformatics, since it allows … Continue reading

Posted in methods, next generation sequencing | Tagged , , , , | 5 Comments