Monthly Archives: May 2012

Calculating pair-wise, unbiased Fst with R:

Calculating Weir and Cockerham’s FST is very useful because it is unbiased with respect to sample size (Weir and Cockerham 1984).  Without adjusting allele frequency estimates with respect to sample sizes, estimates of FST can be upwardly biased (see Waples … Continue reading

Posted in methods, population genetics, software | 16 Comments