Monthly Archives: February 2011

A penny for your method: PCR cleanup

Posted on 19 Feb, 2011 by Brant Faircloth

Very rarely, in scientific research, do we get the opportunity to do less with more. As a result, one thing that we are good at is stretching a dollar. To (hopefully) contribute something back to the struggle, I’ve decided to … Continue reading →

Posted in methods | Tagged | 12 Comments

The Lost Art of the Response to Reviewers

Posted on 11 Feb, 2011 by Tim Vines

OK- this is slightly tongue in cheek, but all this stems from things I’ve seen coming in to MEC. We all do our best to make sure that we evaluate papers from an objective standpoint, but sometimes the response to … Continue reading →

Posted in science publishing | 8 Comments

Riding the Elephant

Posted on 7 Feb, 2011 by Nicholas Crawford

I recently received my first batch of reads from a single paired-end lane run on an [Illumina Hi-Seq](http://www.illumina.com/systems/hiseq_2000.ilmn) instrument. This batch totaled about 20 billion basepairs of DNA sequence, and the associated data files a combined 55.4 gigs of text. … Continue reading →

Posted in bioinformatics, next generation sequencing, software | Tagged , , , , | 9 Comments